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CHOcoCAT - Host cell protein analysis

CHOcoCAT

Targeted measurement and absolute quantification of CHO-derived host cell proteins

Biopharmaceuticals, produced in or purified from appropriate host organisms, require identification and risk analysis of all residual host cell derived contaminations (host cell proteins/HCP). 

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For biopharmaceuticals produced in Chinese Hamster Ovary (CHO) cells, PolyQuant’s CHOcoCAT Kit provides 86 heavy isotope (15N) labeled reference peptides for absolute protein quantification of 29 common and critical CHO-specific host cell proteins (HCP) using LC-MS/MS in nanoFlow.

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Reference: Jones et al. "High-risk" host cell proteins (HCPs): A multi-company collaborative view Biotechnol Bioeng. 2021 Aug;118(8):2870-2885.


Our technology is compatible with various sample preparation protocols (e. g. in-solution, FASP, SP3) and different machine methods (e.g. DIA/SWATH, PRM/MRM, SureQuant) and enables easy setup of multiprotein methods.​

CHOcoCAT box img

Other labeling options and bioinformatic support are available upon request. For package sizes suitable for microFlow, please contact us.

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PolyQuant has established routine protocols for targeted LC-MS/MS measurement of the kit’s peptides. Contact us for sample preparation and measurement service at low cost.

Available Products and Services

CHOcoCAT Service
CHOcoCAT box img

CHOcoCAT

15N-labeled, 2 QconCATs, lyophilized

50 applications

Product code:

CHOcoCAT

Price: € 2,700.00

CHOcoCAT box img

CHOcoCAT-plus

2 QconCATs, 15N labeled and unlabeled, lyophilized

50 applications

Product code:

CHOcoCAT-plus

Price: € 3,450.00

CHOcoCAT box img

Customized

Other labeling options and package sizes are available upon request.

 

Please contact us for more information.

Service

Measurement Service

Benefit from established protocols employing the CHOcoCAT Kit for fast and cost-efficient analysis of your samples.

Special introductory promotion

-50%

Save -50% on your first CHOcoCAT order by using the promo code "MyFirstCHOcoCAT".

 

 

Valid for orders until July 31st, 2025, while supplies last.

© PolyQuant GmbH, Industriestraße 1, 93077 Bad Abbach, Germany

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Collaborations:

Registered Scientist.com Supplier
EuPA collaboration

Certificates:

ISO-certified
Grüner Punkt
FuE Siegel
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