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Protease Profiling

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We provide analytical services, based on in-house developed and established workflows for mass spectrometry analysis of proteases and their natural substrates:

  • Analysis of catalytic and autocatalytic activity

  • Determination of cleavage motifs and specific substrate cleavage sites

  • Cleavage of natural substrates in vivo

More information

Proteases are key regulatory enzymes, involved in numerous physiological processes from processing of pre-proteins to protein destruction, thus regulating fate, localisation and activity of many proteins. To understand protease specificity and activity we have established workflows for mass spectrometry analysis of (auto)-catalytic activity and the cleavage of natural substrates.

Analyse proteases and their natural substrates

Next level protease analysis using in-house developed LC-MS/MS and bioinformatics workflows.

Individual service

Receive customized solutions, independent of host organism or matrix.

Clear timelines, milestones and detailed reporting.

High sensitivity

Stable, accurate and ultra-sensitive protein analysis with high-end instruments without the need for antibodies.

Support

Our experienced team provides consulting and support at every stage of the project.

Contact us now:

Discuss your requirements with our experienced professionals.

E-Mail: info[at]polyquant.com
Phone: +49 (0)9405 96999 10
Fax: +49 (0)9405 96999 28

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